If you ask IT guys, many will tell you that antivirus apps are just another potential threat as they disable OS security stuff and offer system-level access. They will tell you to just trust the OS built-in threat detection and avoid browsing questionable sites (and always use ad blockers, ads are being used to inject trojans and no one's stopping it because of profit) or open stuff that you aren't sure about.
I'm using ESET and all the warnings I got so far were false positives. One threat that was probably serious was blocked by Windows before ESET could get to it.