Not sure about the animation software workflow, but as to noise level, here are some numbers we have established mostly based on user feedback:
Quick preview - 10%
Final with denoising - 5%
Final with no denoising - 2-3%
The sweet spot for denoising amount seems to be something between 0,5 and 0,7 - it gets rid of most of the noise, while steel preserving fine detail.