Something similar like richdirt does, i guess. But instead XYZ, wouldn't it be more logical to use UVW?
p.s. i'm not advocating this request at all ;]
It's harder with UVW afaik, cause you need to have your UV's always oriented certain way. With XYZ bias in VrayDirt, you can do it in wordlspace regardless of UV space.
I remember i used it to make burned train wagon. I just took unwrapped clean model of train wagon, created material of burned metal, and then blended these two materials using VrayDirt modulated by noise map stretched in Z axis upwards. It created those nice black streaks as if flames where burning out of the wagon windows :) And i could then use that blend material and make any material i plug as a base layer appear burned :)
In same manner, if you want to do weathering leaks on concrete for example, you want it based on world axis, as rain falls from top to bottom... not UVs ;)