Definitely stick to Threadripper tallbox.
The X299 platform is only worthy if you have the budget willing to splurge for the 18-core flagship. It does remain technically the superior platform (although with stupid chips gimping stemming from using TIM paste instead of soldering, forcing you to use overkill cooling solution if you want to get any overclock benefits).
For 95perc. of people, Threadripper wins in all aspects.
Regarding your components choice:
- Too low-end, low-wattage PSU. Both Intel X299 and AMD X399 platform are territory for SOLID, gold+ rated 750+ W PSU of reputable brand. This is not even debatable point where compromises can be made. You can go for cheaper non-modular unit for ugly cabling, but that's it.
Intel Optane is pure gimmick if you plan to use it to boost your storage drives. You would need way more than the 16GB for that. But if you intend to use it for System drive boost, don't bother either, and get regular SSD.
NH-14S is rather odd choice for this build. No reason not to go with NH-D15 (can be exchanged for solid CLC 3x120mm units, but nothing less if you go for water cooling)
You seem to make a lot of budget decision. Ignore X299 platform.