The problem with DR is that it runs smooth for some users, and others have issues. Thy are extremely hard to diagnose, and usually we are forced to ask a lot of semi-blind questions to narrow down the possibilities.
Alex, here is one idea:
Could you check if your DrServer is running with administrator privileges? We had a similar case recently where 3ds Max would lose all paths if DrServer was ran in admin mode.
You should be able to check it by going to task manager, locating drserver.exe, right click, properties, compatibility - is the "run this program as admin" checked?
If it is, please try disabling the admin mode as described
here.
I fixed this problem by going changing the permissions on the folder that contained the program.
I added each user that will run that program and gave them "full control" priviledges. That took care of the problem and I left the "run as admin" unchecked.
So here are the instructions:
-locate DrServer.exe, go one step up and select the root folder
-right click, properties, security
-click "edit"
-allow "full control" for all users/groups on the list
-apply
-this should set the permissions to all files and folders inside
-after that, you should be able to go to properties of DrServer.exe and uncheck the "run this program as admin" option - if it's greyed out, you will need to go to "change settings for all users" and uncheck it in there
Please drop me a PM or email if you have any problems with that.