I don't know C4D so I'm not aware of UI differences but in 3ds Max I would:
-about noise: portals are necessary here, in 3ds you make portals by creating single-faced planes with CoronaPortal Mtl and put them in the window holes from the outside. I would also render a GI and direct light passes to see if the noise comes from GI or direct lighting. If it's from GI, I would slightly increase PT samples (32?) - this should improve GI quality without much time loss. If the noise is from direct light, I would decrease PT samples (unless it makes much more noise in GI) and increase direct light samples multiplier
-about AA: if you want better AA, then you should decrease PT samples but it will always be at the cost of GI so see point 1... :)
Generally, adding portals should totally change render times here so what I wrote is simply guessing.