Hello,
would it be possible to provide some clarification on what you mean?
If you mean that after saving a render output to a .cxr and then changing the VirtualBeauty denoising's value and then rendering on top of the .cxr file, the denoising changes, that is the correct behaviour. The renderer will take the newest VirtualBeauty setting and apply that rather than remembering the previous setting when the output was saved. (To reach the same result, you will need not to change the value of VirtualBeauty pass denoising)
Please, let me know if you meant some other thing ;)
Thanks,
Jan